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5HT Receptors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $53.55 | Total: $5,355.00 |
| 1 | 50 | $61.88 | Total: $3,094.00 |
| 1 | 25 | $72.59 | Total: $1,814.75 |
| 1 | 10 | $85.68 | Total: $856.80 |
| 1 | 5 | $101.15 | Total: $505.75 |
Data sheet
| Molecular Formula | C19H28Cl2N6O2 |
| Molecular Weight | 443.37 |
| CAS Numbers | 1645260-76-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.O=C(NCC1CCN(CCCN2N=NC=C2)CC1)C3=CC(Cl)=C(N)C=C3OC |
| References | Lee MJ, et al. Pharmacological profile of DA-6886, a novel 5-HT4 receptor agonist to accelerate colonic motor activity in mice. Eur J Pharmacol. 2014;735 115-122. |
More info
DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels.