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5HT Receptors
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View larger Masupirdine free base
AT11948
CAS 701205-60-9
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $112.05 | Total: $11,205.00 |
| 1 | 50 | $129.48 | Total: $6,474.00 |
| 1 | 25 | $151.89 | Total: $3,797.25 |
| 1 | 10 | $179.28 | Total: $1,792.80 |
| 1 | 5 | $211.65 | Total: $1,058.25 |
Data sheet
| Molecular Formula | C21H24BrN3O3S |
| Molecular Weight | 478.4 |
| CAS Numbers | 701205-60-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=S(=O)(C=1C=CC=CC1Br)N2C=C(C=3C=C(OC)C=CC32)CN4CCN(C)CC4 |
| References | Nirogi R,et al. Discovery and Development of 1-[[2-Bromophenyl]sulfonyl]-5-methoxy-3-[[4-methyl-1-piperazinyl]methyl]-1H-indole Dimesylate Monohydrate [SUVN-502] A Novel, Potent, Selective and Orally Active Serotonin 6 [5-HT6] Receptor Antagonist for Potential Treatment of Alzheimer's Disease. J Med Chem. 2017 Mar 9;60[5] 1843-1859. |
More info
Masupirdine free base (SUVN-502 free base) is an orally available 5-HT6 receptor antagonist that crosses the blood-brain barrier, with a Ki value of 2.04 nM for the human 5-HT6 receptor. It is potent and selective, inhibiting multiple targets, and can be used in the study of neurological disorders such as Alzheimer's disease.