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View larger PRX-07034 hydrochloride
AT8720
CAS 903580-39-2
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $11.70 | Total: $1,170.00 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 5 | $22.10 | Total: $110.50 |
Data sheet
| Molecular Formula | C21H29Cl2N3O4S |
| Molecular Weight | 490.44 |
| CAS Numbers | 903580-39-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.COc1cc(Cl)cc(C(C)Nc2cc(ccc2S(C)(=O)=O)N2CCNCC2)c1OC |
| References | Mohler E G , Baker P M , Gannon K S , et al. The effects of PRX-07034, a novel 5-HT6 antagonist, on cognitive flexibility and working memory in rats[J]. Psychopharmacology, 2012, 220[4] 687-696. |
More info
PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a potent (Ki = 4-8 nM) and highly selective 5-HT(6) receptor antagonist (?100-fold selectivity for the 5-HT(6) receptor compared to 68 other GPCRs, ion channels, and transporters, except D(3) (Ki = 71 nM) and 5-HT(1B) (Ki = 260 nM) receptors.