5HT Receptors

SR 57227 hydrochloride View larger

SR 57227 hydrochloride

AT23394

CAS 77145-61-0

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC10H14ClN3
Molecular Weight248.15
CAS Numbers77145-61-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.NC1CCN(CC1)c1cccc(Cl)n1
ReferencesLi B , Liang W , Sun Z , et al. The Anticonvulsant Effects of SR 57227 on Pentylenetetrazole-Induced Seizure in Mice[J]. Plos One, 2014, 9[4] e93158.

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SR 57227 hydrochloride(SR 57227A ) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier. It has affinities (IC50) varying between 2.8 and 250 nM for 5-HT3 receptor binding sites in rat cortical membranes and on whole NG 108-15 cells or their membranes. Anti-depressant effects.