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View larger Lecozotan HCl
AT27806
CAS 433282-68-9
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $117.30 | Total: $586.50 |
| 1 | 10 | $99.36 | Total: $993.60 |
| 1 | 25 | $84.18 | Total: $2,104.50 |
| 1 | 50 | $71.76 | Total: $3,588.00 |
| 1 | 100 | $62.10 | Total: $6,210.00 |
Data sheet
| Molecular Formula | C28H30ClN5O3 |
| Molecular Weight | 520.02 |
| CAS Numbers | 433282-68-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [C@H](CN(C(=O)C1=CC=C(C#N)C=C1)C2=CC=CC=N2)(C)N3CCN(C4=C5C(=CC=C4)OCCO5)CC3.Cl |
| References | Schechter LE, et al. Lecozotan [SRA-333] a selective serotonin 1A receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties. J Pharmacol Exp Ther. 2005;314[3] 1274-1289. |
More info
Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. Chronic administration of Lecozotan HCl did not induce 5-HT(1A) receptor tolerance or desensitization in a behavioral model demonstrating 5-HT(1A) receptor function.