5HT Receptors

NLX-204 hydrochloride?2170405-10-2 free base? View larger

NLX-204 hydrochloride?2170405-10-2 free base?

AT22379L

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$46.00

$46.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $20.70 Total: $2,070.00
150 $23.92 Total: $1,196.00
125 $28.06 Total: $701.50
110 $33.12 Total: $331.20
15 $39.10 Total: $195.50

Data sheet

Molecular FormulaC20H23Cl2F2N3O2
Molecular Weight446.32
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(N1CCC(CNCCOC2=NC=CC=C2)(CC1)F)C3=CC=C(C(Cl)=C3)F.Cl
ReferencesSniecikowska, Joanna, G?uch-Lutwin, Monika, Bucki, Adam,et al. Novel aryloxyethyl derivatives of 1-[1-benzoylpiperidin-4-yl]methanamine as the Extracellular Regulated Kinases 12 [ERK12] phosphorylation-preferring serotonin 5 HT1A receptor biased agonists with robust antidepressant-like activity[J]. Journal of Medicinal Chemistry, 2019.

More info

NLX-204 hydrochloride is a potent and selective ERK12 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = 10.19).