5HT Receptors

LY 272015 hydrochloride View larger

LY 272015 hydrochloride

AT22948

CAS 172895-15-7

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$47.00

$47.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $21.15 Total: $2,115.00
150 $24.44 Total: $1,222.00
125 $28.67 Total: $716.75
110 $33.84 Total: $338.40
15 $39.95 Total: $199.75

Data sheet

Molecular FormulaC21H25ClN2O2
Molecular Weight372.89
CAS Numbers172895-15-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.O(C1=CC=C(C=C1OC)CC2NCCC=3C=4C=C(C=CC4NC32)C)C
ReferencesRussell A, et al. 5-Hydroxytryptamine[2B] receptor function is enhanced in the N[omega]-nitro-L-arginine hypertensive rat. J Pharmacol Exp Ther. 2002 Oct;303[1] 179-87.

More info

LY 272015 hydrochloride is an orally active and selective 5-HT2B receptor antagonist that displays antihypertensive effects in DOCA-salt hypertensive rats.LY 272015 hydrochloride inhibits 5-HT- or BW723C86-induced ERK2 phosphorylation and attenuates MVIC and Tissue downstream cellular effects of 5HT signaling and can be used to study hepatocellular carcinoma.