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View larger Doxepin hydrochloride
AT1540
CAS 1229-29-4
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Data sheet
| Molecular Formula | C19H22ClNO |
| Molecular Weight | 315.837 |
| CAS Numbers | 1229-29-4 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.CN(C)CCC=C1c2ccccc2COc2ccccc12 |
| References | Ehlert FJ, et al. J Pharmacol Exp Ther. 1990 Apr;253[1] 13-9. |
More info
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.