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View larger ?-Conotoxin MII
ATP2063
CAS 175735-93-0
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $489.60 | Total: $2,448.00 |
| 1 | 10 | $414.72 | Total: $4,147.20 |
| 1 | 25 | $351.36 | Total: $8,784.00 |
| 1 | 50 | $299.52 | Total: $14,976.00 |
| 1 | 100 | $259.20 | Total: $25,920.00 |
Data sheet
| Molecular Formula | C67H103N23O22S4 |
| Molecular Weight | 1710.94 |
| CAS Numbers | 175735-93-0 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1N2[C@@](CCC2)(C(=O)N[C@@H](C(C)C)C(=O)N[C@@]3(C(=O)N[C@@H](CC4=CN=CN4)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC5=CN=CN5)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(N)=O)CSSC[C@@](C(=O)N[C@@H](CO)C(=O)N[C@H]1CC(N)=O)(NC(=O)[C@@H](NC(CN)=O)CSSC3)[H])[H])[H] |
| References | Cartier et al [1996] A new α-conotoxin which targets α3β2 nicotinic acetylcholine receptors. J.Biol.Chem. 271 7522 PMID |
More info
?-Conotoxin MII is a highly potent and selective competitive antagonist for ?3?2 subunit-containing nicotinic receptors (IC50 = 0.5 - 3.5 nM at ?3?2 expressed in Xenopus oocytes). Also potently blocks ?3-containing neuronal nicotinic receptors. Displays > 200-fold selectivity for ?3?2 over ?2?2, ?4?2 and ?3?4.