AChE

?-Conotoxin MII View larger

?-Conotoxin MII

ATP2063

CAS 175735-93-0

More details

Molarity Calculation Cart®

HOW TO ORDER

$576.00

$576.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $259.20 Total: $25,920.00
150 $299.52 Total: $14,976.00
125 $351.36 Total: $8,784.00
110 $414.72 Total: $4,147.20
15 $489.60 Total: $2,448.00

Data sheet

Molecular FormulaC67H103N23O22S4
Molecular Weight1710.94
CAS Numbers175735-93-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1N2[C@@](CCC2)(C(=O)N[C@@H](C(C)C)C(=O)N[C@@]3(C(=O)N[C@@H](CC4=CN=CN4)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC5=CN=CN5)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(N)=O)CSSC[C@@](C(=O)N[C@@H](CO)C(=O)N[C@H]1CC(N)=O)(NC(=O)[C@@H](NC(CN)=O)CSSC3)[H])[H])[H]
ReferencesCartier et al [1996] A new α-conotoxin which targets α3β2 nicotinic acetylcholine receptors. J.Biol.Chem. 271 7522 PMID

More info

?-Conotoxin MII is a highly potent and selective competitive antagonist for ?3?2 subunit-containing nicotinic receptors (IC50 = 0.5 - 3.5 nM at ?3?2 expressed in Xenopus oocytes). Also potently blocks ?3-containing neuronal nicotinic receptors. Displays > 200-fold selectivity for ?3?2 over ?2?2, ?4?2 and ?3?4.