Array
(
)
1
> Activators>AZ3976

Activators

AZ3976 View larger

AZ3976

AOB5270

CAS: 1418747-15-5

 

Chemical Name: tert-Butyl ester 3-(4-Oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-azetidine-1-carboxylate; 1-Boc-3-(4-Oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-azetidine

More details

955 Items

Molarity Calculation Cart®

HOW TO ORDER

$47.54

$47.54 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $40.41 Total: $202.05
110 $34.23 Total: $342.29
125 $29.00 Total: $724.99
150 $24.72 Total: $1,236.04
1100 $21.39 Total: $2,139.30

Data sheet

Molecular FormulaC15H19N5O3
Molecular Weight317.34
CAS Numbers1418747-15-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name1-Boc-3-(4-Oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-azetidine
InChl KeyCKUDSTVQYFRZJW-UHFFFAOYSA-N
InChl CodeInChI=1S/C15H19N5O3/c1-15(2,3)23-14(22)20-7-9(8-20)17-13-18-11-10(12(21)19-13)5-4-6-16-11/h4-6,9H,7-8H2,1-3H3,(H2,16,17,18,19,21)
SMILES CodeO=C1C2=CC=CN=C2N=C(NC3CN(C(OC(C)(C)C)=O)C3)N1
References1) Cazzolli G, Wang F, a Beccara S, Gershenson A, Faccioli P, Wintrode PL. Serpin latency transition at atomic resolution. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15414-9. doi: 10.1073/pnas.1407528111. Epub 2014 Oct 13. PubMed PMID: 25313058; PubMed Central PMCID: PMC4217474.

2) Fjellström O, Deinum J, Sjögren T, Johansson C, Geschwindner S, Nerme V, Legnehed A, McPheat J, Olsson K, Bodin C, Paunovic A, Gustafsson D. Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation. J Biol Chem. 2013 Jan 11;288(2):873-85. doi: 10.1074/jbc.M112.371732. Epub 2012 Nov 15. PubMed PMID: 23155046; PubMed Central PMCID: PMC3543036.

More info

Novel inhibitor of plasminogen activator inhibitor type 1 (PAI-1)