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AZ3976
AOB5270
CAS: 1418747-15-5
Chemical Name: tert-Butyl ester 3-(4-Oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-azetidine-1-carboxylate; 1-Boc-3-(4-Oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-azetidine
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $21.39 | Total: $2,139.30 |
| 1 | 50 | $24.72 | Total: $1,236.04 |
| 1 | 25 | $29.00 | Total: $724.99 |
| 1 | 10 | $34.23 | Total: $342.29 |
| 1 | 5 | $40.41 | Total: $202.05 |
Data sheet
| Molecular Formula | C15H19N5O3 |
| Molecular Weight | 317.34 |
| CAS Numbers | 1418747-15-5 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 1-Boc-3-(4-Oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-azetidine |
| InChl Key | CKUDSTVQYFRZJW-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C15H19N5O3/c1-15(2,3)23-14(22)20-7-9(8-20)17-13-18-11-10(12(21)19-13)5-4-6-16-11/h4-6,9H,7-8H2,1-3H3,(H2,16,17,18,19,21) |
| SMILES Code | O=C1C2=CC=CN=C2N=C(NC3CN(C(OC(C)(C)C)=O)C3)N1 |
| References | 1) Cazzolli G, Wang F, a Beccara S, Gershenson A, Faccioli P, Wintrode PL. Serpin latency transition at atomic resolution. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15414-9. doi: 10.1073/pnas.1407528111. Epub 2014 Oct 13. PubMed PMID: 25313058; PubMed Central PMCID: PMC4217474. 2) Fjellström O, Deinum J, Sjögren T, Johansson C, Geschwindner S, Nerme V, Legnehed A, McPheat J, Olsson K, Bodin C, Paunovic A, Gustafsson D. Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation. J Biol Chem. 2013 Jan 11;288(2):873-85. doi: 10.1074/jbc.M112.371732. Epub 2012 Nov 15. PubMed PMID: 23155046; PubMed Central PMCID: PMC3543036. |
More info
Novel inhibitor of plasminogen activator inhibitor type 1 (PAI-1)