ADC cytotoxin

Aldoxorubicin hydrochloride View larger

Aldoxorubicin hydrochloride

AT11090L1

CAS 1361563-03-2

More details

Molarity Calculation Cart®

HOW TO ORDER

$48.00

$48.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $21.60 Total: $2,160.00
150 $24.96 Total: $1,248.00
125 $29.28 Total: $732.00
110 $34.56 Total: $345.60
15 $40.80 Total: $204.00

Data sheet

Molecular FormulaC37H43ClN4O13
Molecular Weight787.21
CAS Numbers1361563-03-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC=1C2=C([C@@H](O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C[C@@](C(=NNC(CCCCCN4C(=O)C=CC4=O)=O)CO)(O)C2)C(O)=C5C1C(=O)C=6C(C5=O)=C(OC)C=CC6.Cl
ReferencesEric Sanchez, et al. Anti-Myeloma Effects of the Novel Anthracycline Derivative INNO-206. Clin Cancer Res.2012 18; 3856.

More info

Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibits potent antitumor activities in various cancer cell lines and in murine tumor models.