ADC Linker

Fmoc-8-amino-3,6-dioxaoctanoic acid View larger

Fmoc-8-amino-3,6-dioxaoctanoic acid

AT15304

CAS 166108-71-0

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$27.00

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Data sheet

Molecular FormulaC21H23NO6
Molecular Weight385.41
CAS Numbers166108-71-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC(=O)COCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12
ReferencesNakamura A, et al. Chemogenetic Control of Protein Anchoring to Endomembranes in Living Cells with Lipid-Tethered Small Molecules. Biochemistry. 2020 Jan 21;59[2] 205-211.

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Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker for the synthesis of PROTACs.