Adrenoceptor

Salbutamol View larger

Salbutamol

AT1139

CAS 18559-94-9

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$36.00

$36.00 per 100 mg

Data sheet

Molecular FormulaC13H21NO3
Molecular Weight239.31
CAS Numbers18559-94-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)(C)NCC(O)C1=CC(CO)=C(O)C=C1
ReferencesBrichetto L, et al. Am J Physiol Lung Cell Mol Physiol. 2003 Jan;284[1] L133-9.

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Salbutamol (Albuterol) stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3', 5'-adenosine monophosphate (cAMP). Salbutamol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Increased cAMP concentrations relax the bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent, Salbutamol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.