Adrenoceptor

Fiduxosin View larger

Fiduxosin

AT11286

CAS 208993-54-8

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$595.00

$595.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $267.75 Total: $26,775.00
150 $309.40 Total: $15,470.00
125 $362.95 Total: $9,073.75
110 $428.40 Total: $4,284.00
15 $505.75 Total: $2,528.75

Data sheet

Molecular FormulaC30H29N5O4S
Molecular Weight555.65
CAS Numbers208993-54-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1C2=C(C=3C(S2)=NC=C(N3)C4=CC=CC=C4)NC(=O)N1CCCCN5C[C@@]6([C@](C5)(COC=7C6=C(OC)C=CC7)[H])[H]
ReferencesBrune ME, et al. Effect of fiduxosin, an antagonist selective for alpha[1A]- and alpha[1D]-adrenoceptors, on intraurethral and arterial pressure responses in conscious dogs. J Pharmacol Exp Ther. 2002 Feb;300[2] 487-94.

More info

Fiduxosin is a selective and potent ?1-adrenoceptor antagonist with inhibitory effects on ?1a-adrenoceptor, ?1b-adrenoceptor and ?1d-adrenoceptor, with Ki values of 0.160 nM, 24.9 nM and 0.920 nM, respectively. Fiduxosin can be used for the treatment of benign prostatic hyperplasia.