Allosteric

PKUMDL-WQ-2101 View larger

PKUMDL-WQ-2101

AOB8011

CAS: 304481-72-9 (2095878-12-7)

 

Chemical Name: (E)-2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $4.95 Total: $495.00
150 $5.72 Total: $286.00
125 $6.71 Total: $167.75
110 $7.92 Total: $79.20
15 $9.35 Total: $46.75

Data sheet

Molecular FormulaC14H11N3O6
Molecular Weight317.25
CAS Numbers304481-72-9 (2095878-12-7)
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilitySoluble to 100 mM in DMSO
Purity98% by HPLC
SynonymPKUMDL WQ 2101
IUPAC/Chemical Name(E)-2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide
InChl KeyOXONIXZPWKJHMW-VIZOYTHASA-N
InChl CodeInChI=1S/C14H11N3O6/c18-10-2-3-11(13(20)6-10)14(21)16-15-7-8-5-9(17(22)23)1-4-12(8)19/h1-7,18-20H,(H,16,21)/b15-7+
SMILES CodeO=C(N/N=C/C1=CC([N+]([O-])=O)=CC=C1O)C2=CC=C(O)C=C2O
ReferencesWang et al (2017) Rational design of selective allosteric inhibitors of PHGDH and serine synthesis with anti-tumor activity. Cell Chem.Biol. 24 55 PMID: 28042046

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Novel selective allosteric inhibitor of PHGDH and serine synthesis with anti-tumor activity, binding to site I