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View larger UoS-12258
AOB17747
CAS: 875927-64-3
Chemical Name: N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide
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| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $16.15 | Total: $80.75 |
| 1 | 10 | $13.68 | Total: $136.80 |
| 1 | 25 | $11.59 | Total: $289.75 |
| 1 | 50 | $9.88 | Total: $494.00 |
| 1 | 100 | $8.55 | Total: $855.00 |
Data sheet
| Molecular Formula | C17H19FN2O2S |
| Molecular Weight | 334.41 |
| CAS Numbers | 875927-64-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | UoS 12258; UoS12258; UoS-12258 |
| IUPAC/Chemical Name | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide |
| InChl Key | QXQSUBKWSHMXDP-INIZCTEOSA-N |
| InChl Code | InChI=1S/C17H19FN2O2S/c1-11(2)23(21,22)20-16-8-13-4-3-12(7-15(13)9-16)14-5-6-17(18)19-10-14/h3-7,10-11,16,20H,8-9H2,1-2H3/t16-/m0/s1 |
| SMILES Code | CC(S(=O)(N[C@H]1CC2=CC=C(C3=CN=C(C=C3)F)C=C2C1)=O)C |
| References | 1) Ward et al (2010) Discovery of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a novel clinical AMPA receptor positive modulator. J.Med.Chem. 53 5801 PMID: 20614889 2) Ward et al (2017) Pharmacological characterization of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2, 3-dihydro-1H-inden-2-yl]-2-propanesulfonamide: a novel, clinical AMPA receptor positive allosteric modulator. Br.J.Pharmacol. 174 370 PMID: 28009436 |
| PubChem ID | 46398805 |
More info
Novel positive allosteric modulator (PAM) of AMPA receptors