Alzheimer's Disease

JAY2-22-33 View larger

JAY2-22-33

AOB2333

CAS: 121489-14-3

 

Chemical Name: JAY-2-22-33; 2-(Methyl-pyridin-3-ylmethyl-amino)-ethanol

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$27.00

$27.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $12.15 Total: $1,215.00
50 $14.04 Total: $702.00
25 $16.47 Total: $411.75
10 $19.44 Total: $194.40
5 $22.95 Total: $114.75

Data sheet

Molecular FormulaC9H14N2O
Molecular Weight166.22
CAS Numbers121489-14-3
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name2-(methyl(pyridin-3-ylmethyl)amino)ethan-1-ol
InChl KeyAONUOBNHKYQJIO-UHFFFAOYSA-N
InChl CodeInChI=1S/C9H14N2O/c1-11(5-6-12)8-9-3-2-4-10-7-9/h2-4,7,12H,5-6,8H2,1H3
SMILES CodeCN(CCO)CC1=CC=CN=C1
References1) Keowkase R, Aboukhatwa M, Adam BL, Beach JW, Terry AV Jr, Buccafussco JJ, Luo Y. Neuroprotective effects and mechanism of cognitive-enhancing choline analogs JWB 1-84-1 and JAY 2-22-33 in neuronal culture and Caenorhabditis elegans. Mol Neurodegener. 2010 Dec 16;5:59.

2) Buccafusco JJ, Beach JW, Terry AV Jr. Desensitization of nicotinic acetylcholine receptors as a strategy for drug development. J Pharmacol Exp Ther. 2009 Feb;328(2):364-70

More info

Novel neuroprotective agent, significantly reducing Aβ toxicity by delaying paralysis and improving cognitive performances in a transgenic mouse model of AD