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Tabersonine
AOB5150
CAS: 4429-63-4
Chemical Name: Methyl (5alpha,19alpha)-16-methoxy-8-oxo-2,3,6,7-tetradehydroaspidospermidine-3-carboxylate
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $6.75 | Total: $675.00 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 5 | $12.75 | Total: $63.75 |
Data sheet
| Molecular Formula | C21H24N2O2 |
| Molecular Weight | 336.4 |
| CAS Numbers | 4429-63-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | (–)-Tabersonine |
| IUPAC/Chemical Name | (5α,12R,19α)-2,3,6,7-tetradehydro-aspidospermidine-3-carboxylic acid, methyl ester |
| InChl Key | FNGGIPWAZSFKCN-ACRUOGEOSA-N |
| InChl Code | InChI=1S/C21H24N2O2/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2/h4-9,19,22H,3,10-13H2,1-2H3/t19-,20-,21-/m0/s1 |
| SMILES Code | O=C(OC)C1=C2[C@]3(C4=CC=CC=C4N2)[C@@]5([H])N(CC3)CC=C[C@@]5(CC)C1 |
| References | 1) 1. Kai, T., Zhang, L., Wang, X., et al. Tabersonine inhibits amyloid fibril formation and cytotoxicity of Aβ(1-42). ACS Chem. Neurosci. 6(6), 879-888 (2015). 2) Qu, Y., Easson, M.L.A.E., Froese, J., et al. Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast. Proc. Natl. Acad. Sci. U.S.A. 112(19), 6224-6229 (2015). |
More info
Inhibitor of Amyloid Fibril Formation and Cytotoxicity of Aβ(1-42), permeating the blood-brain barrier
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