Alzheimer's Disease

2-PMAP View larger

2-PMAP

AOB1080

CAS No: 102212-26-0

 

Chemical Name: 2-[[(o-Hydroxyphenyl)amino]methyl]pyridine

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$13.00

$13.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $5.85 Total: $585.00
150 $6.76 Total: $338.00
125 $7.93 Total: $198.25
110 $9.36 Total: $93.60
15 $11.05 Total: $55.25

Data sheet

Molecular FormulaC12H12N2O
Molecular Weight200.24
CAS Numbers102212-26-0
Storage Condition4C at solid form for three years
SolubilityDMSO
SynonymARN2966
IUPAC/Chemical Name2-[(2-pyridinylmethyl)amino]-phenol
InChl KeyGXJRVWZNMZGWAQ-UHFFFAOYSA-N
InChl CodeInChI=1S/C12H12N2O/c15-12-7-2-1-6-11(12)14-9-10-5-3-4-8-13-10/h1-8,14-15H,9H2
SMILES CodeOC1=CC=CC=C1NCC2=NC=CC=C2
References1) Yodeji Asuni, et al. An APP translation modulator ARN2966 reduces BETA-AMYLOID deposition and prevents memory deficits in ALZHEIMER'S DISEASE transgenic mice. Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 2012.

2) Asuni, A.A., Guridi, M., Pankiewicz, J.E., et al. Modulation of APP expression reduces Aβ deposition in a mouse model. Ann. Neurol. 75(5), 684-699 (2014).

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Novel modulator of amyloid precursor protein expression, reducing β-amyloid deposition