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Alzheimer's Disease
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View larger F-cromolyn
AOB19437
CAS: 1236211-78-1
Chemical Name: 5,5'-((2-Fluoropropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylic acid)
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $75.65 | Total: $378.25 |
| 1 | 10 | $64.08 | Total: $640.80 |
| 1 | 25 | $54.29 | Total: $1,357.25 |
| 1 | 50 | $46.28 | Total: $2,314.00 |
| 1 | 100 | $40.05 | Total: $4,005.00 |
Data sheet
| Molecular Formula | C23H15FO10 |
| Molecular Weight | 470.35 |
| CAS Numbers | 1236211-78-1 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| Synonym | Fcromolyn |
| IUPAC/Chemical Name | 5,5'-((2-Fluoropropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylic acid) |
| References | 1) Timothy Shoup et al., Fluorinated Cromolyn Derivatives for Potential Alzheimer’s Disease Treatment, Journal of Nuclear Medicine Vol. 60, Issue supplement 1 May 1, 2019 |
More info
Novel potent anti-Alzheimer agent, reducing secretion of collagen XVIII, fibronectin, and tenascin-c, also reducing pro-inflammatory proteins PLP1, PELP1, HSP90, IL-2, GRO-α, Eotaxin, and VEGF-Α, while promoting secretion of anti-inflammatory IL-4 in HMC3 microglia, targeting multiple proteins upstream of PI3K/Akt/mTOR, NF-κB, and GSK-3β signaling pathways to affect cytokine, chemokine, and fibrosis-related protein expression