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Alzheimer's Disease
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View larger Avagacestat
AT6249
CAS 1146699-66-2
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $40.80 | Total: $204.00 |
| 1 | 10 | $34.56 | Total: $345.60 |
| 1 | 25 | $29.28 | Total: $732.00 |
| 1 | 50 | $24.96 | Total: $1,248.00 |
| 1 | 100 | $21.60 | Total: $2,160.00 |
Data sheet
| Molecular Formula | C20H17ClF4N4O4S |
| Molecular Weight | 520.89 |
| CAS Numbers | 1146699-66-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC(=O)[C@@H](CCC(F)(F)F)N(Cc1ccc(cc1F)-c1ncon1)S(=O)(=O)c1ccc(Cl)cc1 |
| References | Gillman KW, et al. Med Chem Lett, 2010, 1 [3], 120 |
More info
Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable ?-secretase inhibitor of A?40 and A?42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.