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> Alzheimer's Disease>Qingyangshengenin B

Alzheimer's Disease

Qingyangshengenin B View larger

Qingyangshengenin B

ATMS1461

CAS 106758-54-7

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$71.00

$71.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $60.35 Total: $301.75
110 $51.12 Total: $511.20
125 $43.31 Total: $1,082.75
150 $36.92 Total: $1,846.00
1100 $31.95 Total: $3,195.00

Data sheet

Molecular FormulaC49H78O16
Molecular Weight923.13
CAS Numbers106758-54-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO[C@]12[C@](C)([C@H](OC(C=C(C(C)C)C)=O)C[C@]3([C@@]1(O)CC=C4[C@]3(C)CC[C@H](O[C@H]5C[C@H](OC)[C@H](O[C@H]6C[C@H](OC)[C@H](O[C@H]7C[C@@H](OC)[C@H](O)[C@@H](C)O7)[C@@H](C)O6)[C@@H](C)O5)C4)[H])[C@@](C(C)=O)(O)CC2
ReferencesYang, Jie, Wan, et al. The Lifespan-Promoting Effect of Otophylloside B in Caenorhabditis elegans[J]. Natural Products and Bioprospecting, 2015, 5[4] 177-183.

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Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against A? toxicity, which decreases A? deposition by decreasing the expression of A? at the mRNA level. Qingyangshengenin B has antiepileptic and anti-aging effects, it can extend lifespan, increase heat stress-resistance, delay body paralysis, and increase the chemotaxis response in C. elegans models of Alzheimer's disease. Otophylloside B can suppress the seizure-like locomotor activity caused by pentylenetetrazole in zebrafish.