Alzheimer's Disease

PBD-150 View larger

PBD-150

AT7905

CAS 790663-33-1

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HOW TO ORDER

$43.00

$43.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $19.35 Total: $1,935.00
150 $22.36 Total: $1,118.00
125 $26.23 Total: $655.75
110 $30.96 Total: $309.60
15 $36.55 Total: $182.75

Data sheet

Molecular FormulaC15H20N4O2S
Molecular Weight320.41
CAS Numbers790663-33-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1ccc(NC(=S)NCCCn2ccnc2)cc1OC
ReferencesHuang, K.-F, Liaw, S.-S, Huang, W.-L,et al. Structures of Human Golgi-resident Glutaminyl Cyclase and Its Complexes with Inhibitors Reveal a Large Loop Movement upon Inhibitor Binding[J]. Journal of Biological Chemistry, 286[14] 12439-12449.

More info

PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)