Antibacterial

G-418 disulfate View larger

G-418 disulfate

AT6512

CAS 108321-42-2

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Data sheet

Molecular FormulaC20H40N4O10
Molecular Weight692.71
CAS Numbers108321-42-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)OC[C@]1(C)O
ReferencesDelrue I, et al. Determination of the Selection Capacity of Antibiotics for Gene Selection. Biotechnol J. 2018 Aug;13[8] e1700747.

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G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic that selectively inhibits eukaryotic protein synthesis by blocking peptide chain elongation.