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Antibacterial

NITD-916 View larger

NITD-916

AT60774

CAS 1614262-83-7

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$298.00

$298.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $253.30 Total: $1,266.50
110 $214.56 Total: $2,145.60
125 $181.78 Total: $4,544.50
150 $154.96 Total: $7,748.00
1100 $134.10 Total: $13,410.00

Data sheet

Molecular FormulaC20H25NO2
Molecular Weight311.42
CAS Numbers1614262-83-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC1=C(C2=CC=CC=C2)C(=O)NC(CC3CCC(C)(C)CC3)=C1
ReferencesManjunatha UH, et al. Direct inhibitors of InhA are active against Mycobacterium tuberculosis. Sci Transl Med. 2015 Jan 7;7[269] 269ra3.

More info

NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NADH, preventing access to the fatty acyl substrate-binding pocket.NITD-916 exhibits antituberculosis activity.