Antibacterial

BPH-1358 View larger

BPH-1358

AT10586L

CAS 5352-53-4

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$113.00

$113.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $50.85 Total: $5,085.00
150 $58.76 Total: $2,938.00
125 $68.93 Total: $1,723.25
110 $81.36 Total: $813.60
15 $96.05 Total: $480.25

Data sheet

Molecular FormulaC32H30Cl2N6O2
Molecular Weight601.53
CAS Numbers5352-53-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(C1=CC=C(C2=CC=C(C(NC3=CC=CC(C4=NCCN4)=C3)=O)C=C2)C=C1)NC5=CC=CC(C6=NCCN6)=C5.[H]Cl.[H]Cl
ReferencesZhu W, et al. Antibacterial drug leads DNA and enzyme multitargeting. J Med Chem. 2015 Feb 12;58[3] 1215-27.

More info

BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 ?M and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ngmL)[1][2].