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Antibacterial

LpxH-IN-AZ1 View larger

LpxH-IN-AZ1

AT11876

CAS 901260-40-0

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$43.00

$43.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $36.55 Total: $182.75
110 $30.96 Total: $309.60
125 $26.23 Total: $655.75
150 $22.36 Total: $1,118.00
1100 $19.35 Total: $1,935.00

Data sheet

Molecular FormulaC21H22F3N3O3S
Molecular Weight453.48
CAS Numbers901260-40-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(C)(=O)N1C=2C(=CC(S(=O)(=O)N3CCN(CC3)C4=CC(C(F)(F)F)=CC=C4)=CC2)CC1
ReferencesCho J, et al. Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics. Proc Natl Acad Sci U S A. 2020 Feb 25;117[8] 4109-4116.

More info

LpxH-IN-AZ1 is a potent inhibitor of the UDP-2,3-diacylglucosamine pyrophosphate hydrolase, LpxH, and sulfonylpiperazine compounds.LpxH-IN-AZ1 exhibits antimicrobial activity and inhibits Klebsiella pneumoniae with an IC50 of 0.36 ?M.