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View larger Bafilomycin A1
AT6740
CAS 88899-55-2
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $207.40 | Total: $1,037.00 |
| 1 | 10 | $175.68 | Total: $1,756.80 |
| 1 | 25 | $148.84 | Total: $3,721.00 |
| 1 | 50 | $126.88 | Total: $6,344.00 |
| 1 | 100 | $109.80 | Total: $10,980.00 |
Data sheet
| Molecular Formula | C35H58O9 |
| Molecular Weight | 622.83 |
| CAS Numbers | 88899-55-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H][C@@]1(OC(=O)C(OC)=CC(C)=C[C@@H](C)[C@@H](O)[C@@H](C)CC(C)=CC=C[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](O)[C@H](C)[C@H](O1)C(C)C |
| References | Ohta T, et al. Bafilomycin A1 induces apoptosis in the human pancreatic cancer cell line Capan-J Pathol. 1998 Jul;185[3] 324-30. |
More info
Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase inhibitor (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of the late phase of autophagy, blocking the fusion of autophagosomes with lysosomes. Bafilomycin A1 also induces apoptosis.