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Antibacterial

Ofloxacin View larger

Ofloxacin

AT0902

CAS 82419-36-1

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Data sheet

Molecular FormulaC18H20FN3O4
Molecular Weight361.37
CAS Numbers82419-36-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)OCC(C)N3C=C1C(O)=O
ReferencesDivo AA, et al. Antimicrob Agents ChemOthers. 1988 Aug;32[8] 1182-6.

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Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species.