Antiviral

GLP-26 View larger

GLP-26

AT11409

CAS 2133017-36-2

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$93.00

$93.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $41.85 Total: $4,185.00
150 $48.36 Total: $2,418.00
125 $56.73 Total: $1,418.25
110 $66.96 Total: $669.60
15 $79.05 Total: $395.25

Data sheet

Molecular FormulaC19H17F2N3O3
Molecular Weight373.35
CAS Numbers2133017-36-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1c(C(=O)C(=O)NCC#C)c(C)n(C)c1C(=O)Nc1ccc(F)c(F)c1
ReferencesNijampatnam B, et al. Recent advances in the development of HBV capsid assembly modulators. Curr Opin Chem Biol. 2019 Jun;50 73-79.

More info

GLP-26, an HBV capsid assembly regulator (CAM), inhibits HBV DNA replication (IC50=3 nM) in the Hep AD38 system and reduces cccDNA by >90% at 1 ?M. GLP-26 disrupts the encapsidation of pregenomic RNA, leading to nucleocapsid disassembly and reducing the cccDNA library.