Antiviral

SARS-CoV-2 nsp13-IN-1 View larger

SARS-CoV-2 nsp13-IN-1

AT62413

CAS 1005304-44-8

More details

Molarity Calculation Cart®

HOW TO ORDER

$33.00

$33.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $14.85 Total: $1,485.00
150 $17.16 Total: $858.00
125 $20.13 Total: $503.25
110 $23.76 Total: $237.60
15 $28.05 Total: $140.25

Data sheet

Molecular FormulaC27H20N4O2
Molecular Weight432.47
CAS Numbers1005304-44-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC1=NC2=C(C=CC=N2)C(=O)N1C1=CC=C(NC(=O)C2=CC=C(C=C2)C2=CC=CC=C2)C=C1
ReferencesYazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.

More info

SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent inhibitor of nsp13 (non-structural protein 13), selectively inhibiting nsp13 ssDNA+ATPase with an IC50 of 6 ?M, but not ssDNA-ATPase, and can be used to study COVID-19.