Antiviral

Octyl gallate View larger

Octyl gallate

AT2S1865

CAS 1034-01-1

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Data sheet

Molecular FormulaC15H22O5
Molecular Weight282.33
CAS Numbers1034-01-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(OCCCCCCCC)(=O)C1=CC(O)=C(O)C(O)=C1
ReferencesSales, SM , Roy, A , Antony, L , et al. Octyl gallate and gallic acid isolated from, Terminalia bellarica, regulates normal cell cycle in human breast cancer cell lines[J]. Biomedicine & Pharmacotherapy, 2018, 103 1577-1584.

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1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Octyl Gallate shows antimicrobial activity against H. pylori, with a minimum inhibitory concentration (MIC) value of 125 ugmL. 4. Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease.5. Octyl Gallate is a potential anticancer agent, it exhibited decreased MCF-7 & MDA-MB-231 survival and induced apoptosis, with IC50 value of 40 uM. 6. Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) has antiviral activity, it shows an inhibitory effect on the growth of herpes simplex virus type 1 (HSV-1) in HEp-2 or Vero cells. 7. Octyl gallate shows antifungal activity against Saccharomyces cerevisiae ATCC7754 and Zygosaccharomyces bailii ATCC 60483.