Apoptosis

Decitabine View larger

Decitabine

AT1508

CAS 2353-33-5

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$33.00

$33.00 per 100 mg

Data sheet

Molecular FormulaC8H12N4O4
Molecular Weight228.21
CAS Numbers2353-33-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeNc1ncn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1
ReferencesZhang G, et al. Decitabine inhibits the proliferation of human T-cell acute lymphoblastic leukemia molt4 cells and promotes apoptosis partly by regulating the PI3KAKTmTOR pathway. Oncol Lett. 2021 May;21[5] 340.

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Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis.