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> Apoptosis>ABT-510 acetate

Apoptosis

ABT-510 acetate View larger

ABT-510 acetate

AT24997

CAS 442526-87-6

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$46.00

$46.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $39.10 Total: $195.50
110 $33.12 Total: $331.20
125 $28.06 Total: $701.50
150 $23.92 Total: $1,196.00
1100 $20.70 Total: $2,070.00

Data sheet

Molecular FormulaC48H87N13O13
Molecular Weight1054.28
CAS Numbers442526-87-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(C)(O)=O.C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC(CNC(CN(C(C)=O)C)=O)=O)[C@H](C)C)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)CCC)=O)[C@H](CC)C)=O)CCCNC(=N)N)(=O)N1[C@H](C(NCC)=O)CCC1
ReferencesGreenaway J, et al. ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer. Mol Cancer Ther. 2009;8[1] 64-74.

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ABT-510 acetate is an endogenous anti-angiogenic TSP peptide inhibitor, a thrombospondin analog, with anti-inflammatory, anti-cancer and anti-angiogenic activity that induces apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer.ABT-510 acetate reduces angiogenesis and inflammatory responses in a mouse model of inflammatory bowel disease. ABT-510 acetate reduces angiogenesis and inflammation in mouse models of inflammatory bowel disease (IBD) and can be used in cancer research, particularly in epithelial ovarian cancer, as well as in inflammatory bowel disease (IBD).