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Apoptosis
- Protein Control Ligand
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View larger (R)-CR8 trihydrochloride
AT12617
CAS 1786438-30-9
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HOW TO ORDER
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $12.15 | Total: $1,215.00 |
| 1 | 50 | $14.04 | Total: $702.00 |
| 1 | 25 | $16.47 | Total: $411.75 |
| 1 | 10 | $19.44 | Total: $194.40 |
| 1 | 5 | $22.95 | Total: $114.75 |
Data sheet
| Molecular Formula | C24H32Cl3N7O |
| Molecular Weight | 540.92 |
| CAS Numbers | 1786438-30-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cl.Cl.CC[C@H](CO)Nc1nc(NCc2ccc(cc2)-c2ccccn2)c2ncn(C(C)C)c2n1 |
| References | Bettayeb K, et al. CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases. Oncogene. 2008 Oct 2;27[44] 5797-807. |
More info
(R)-CR8 trihydrochloride (CR8, (R)-Isomer trihydrochloride) is a CDK12579 inhibitor that acts as a molecular glue degrader with neuroprotective activity and induces apoptosis.