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View larger Imidazole ketone erastin
AT5523
CAS 1801530-11-9
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HOW TO ORDER
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $27.00 | Total: $2,700.00 |
| 1 | 50 | $31.20 | Total: $1,560.00 |
| 1 | 25 | $36.60 | Total: $915.00 |
| 1 | 10 | $43.20 | Total: $432.00 |
| 1 | 5 | $51.00 | Total: $255.00 |
Data sheet
| Molecular Formula | C35H35ClN6O5 |
| Molecular Weight | 655.14 |
| CAS Numbers | 1801530-11-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)Oc1ccc(cc1-n1c(CN2CCN(CC2)C(=O)COc2ccc(Cl)cc2)nc2ccccc2c1=O)C(=O)Cn1ccnc1 |
| References | Larraufie MH, et al. Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility. Bioorg Med Chem Lett. 2015 Nov 1;25[21] 4787-4792. |
More info
Imidazole ketone erastin (IKE) is an ferroptosis inducer with inhibitory effects on system Xc-cystineglutamate transporter proteins. Imidazole ketone erastin has antitumor activity and induces glutathione depletion and lipid peroxidation.