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Apoptosis
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View larger Nevanimibe hydrochloride
AT12225L
CAS 133825-81-7
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $33.30 | Total: $3,330.00 |
| 1 | 50 | $38.48 | Total: $1,924.00 |
| 1 | 25 | $45.14 | Total: $1,128.50 |
| 1 | 10 | $53.28 | Total: $532.80 |
| 1 | 5 | $62.90 | Total: $314.50 |
Data sheet
| Molecular Formula | C27H40ClN3O |
| Molecular Weight | 458.08 |
| CAS Numbers | 133825-81-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(CCCC1)c1ccc(cc1)N(C)C |
| References | LaPensee CR, et al. ATR-101, a Selective and Potent Inhibitor of Acyl-CoA Acyltransferase 1, Induces Apoptosis in H295R Adrenocortical Cells and in the Adrenal Cortex of Dogs. Endocrinology. 2016 May;157[5] 1775-88. |
More info
Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active, selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) with an EC50 of 9 nM.