Apoptosis

BAY 61-3606 View larger

BAY 61-3606

AT4263

CAS 732983-37-8

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$43.00

$43.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $19.35 Total: $1,935.00
150 $22.36 Total: $1,118.00
125 $26.23 Total: $655.75
110 $30.96 Total: $309.60
15 $36.55 Total: $182.75

Data sheet

Molecular FormulaC20H18N6O3
Molecular Weight390.4
CAS Numbers732983-37-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN(C=1N2C(C=C(N1)C3=CC(OC)=C(OC)C=C3)=NC=C2)C4=C(C(N)=O)C=CC=N4
ReferencesYamamoto N, et al. The orally available spleen tyrosine kinase inhibitor 2-[7-[3,4-dimethoxyphenyl]-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide dihydrochloride [BAY 61-3606] blocks antigen-induced airway inflammation in rodents. J Pharmacol Exp Ther. 2003 Sep;306[3] 1174-81

More info

BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src.