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Apoptosis
- Protein Control Ligand
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View larger VU 0364739 hydrochloride
AT23512
CAS 1244640-48-9
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $121.55 | Total: $607.75 |
| 1 | 10 | $102.96 | Total: $1,029.60 |
| 1 | 25 | $87.23 | Total: $2,180.75 |
| 1 | 50 | $74.36 | Total: $3,718.00 |
| 1 | 100 | $64.35 | Total: $6,435.00 |
Data sheet
| Molecular Formula | C26H28ClFN4O2 |
| Molecular Weight | 482.98 |
| CAS Numbers | 1244640-48-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.O=C(NCCN1CCC2(C(=O)NCN2C=3C=CC=C(F)C3)CC1)C=4C=CC=5C=CC=CC5C4 |
| References | Lavieri RR, et al. Design, synthesis, and biological evaluation of halogenated N-[2-[4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]benzamides discovery of an isoform-selective small molecule phospholipase D2 inhibitor. J Med Chem. 2010 Sep 23;53[18] 6706-19. |
More info
VU 0364739 hydrochloride (VU 0364739 HCl) is a selective and potent inhibitor of phospholipase D2 (PLD2) with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively.VU 0364739 hydrochloride exhibits potential anticancer activity and induces apoptosis. VU 0364739 hydrochloride has potential anticancer activity, induces apoptosis, and can be used in the study of cancer and metabolic-related diseases.