Apoptosis

VU 0364739 hydrochloride View larger

VU 0364739 hydrochloride

AT23512

CAS 1244640-48-9

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$143.00

$143.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $64.35 Total: $6,435.00
150 $74.36 Total: $3,718.00
125 $87.23 Total: $2,180.75
110 $102.96 Total: $1,029.60
15 $121.55 Total: $607.75

Data sheet

Molecular FormulaC26H28ClFN4O2
Molecular Weight482.98
CAS Numbers1244640-48-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.O=C(NCCN1CCC2(C(=O)NCN2C=3C=CC=C(F)C3)CC1)C=4C=CC=5C=CC=CC5C4
ReferencesLavieri RR, et al. Design, synthesis, and biological evaluation of halogenated N-[2-[4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]benzamides discovery of an isoform-selective small molecule phospholipase D2 inhibitor. J Med Chem. 2010 Sep 23;53[18] 6706-19.

More info

VU 0364739 hydrochloride (VU 0364739 HCl) is a selective and potent inhibitor of phospholipase D2 (PLD2) with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively.VU 0364739 hydrochloride exhibits potential anticancer activity and induces apoptosis. VU 0364739 hydrochloride has potential anticancer activity, induces apoptosis, and can be used in the study of cancer and metabolic-related diseases.