Apoptosis

TMI-1 View larger

TMI-1

AT28985

CAS 287403-39-8

More details

Molarity Calculation Cart®

HOW TO ORDER

$30.00

$30.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.50 Total: $1,350.00
150 $15.60 Total: $780.00
125 $18.30 Total: $457.50
110 $21.60 Total: $216.00
15 $25.50 Total: $127.50

Data sheet

Molecular FormulaC17H22N2O5S2
Molecular Weight398.5
CAS Numbers287403-39-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO
ReferencesZhang Y, et al. Identification and characterization of 4-[[4-[2-butynyloxy]phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-[3S]thiomorpholinecarboxamide [TMI-1], a novel dual tumor necrosis factor-alpha-converting enzymematrix metalloprotease inhibitor for the treatment of rheumatoid arthritis. J Pharmacol Exp Ther. 2004;309[1] 348-355.

More info

TMI-1 (WAY-171318), a novel orally active inhibitor of ADAM17 (TACE) and MMP, induces tumor apoptosis in a breast cancer.