Apoptosis

STAT3-IN-1 View larger

STAT3-IN-1

AT13009

CAS 2059952-75-7

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$47.00

$47.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $21.15 Total: $2,115.00
150 $24.44 Total: $1,222.00
125 $28.67 Total: $716.75
110 $33.84 Total: $338.40
15 $39.95 Total: $199.75

Data sheet

Molecular FormulaC28H29NO6
Molecular Weight475.53
CAS Numbers2059952-75-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1cc(OC)cc(C=Cc2ccc(NC(=O)C=Cc3cc(OC)c(OC)c(OC)c3)cc2)c1
ReferencesLi S, et al. Discovery of oral-available resveratrol-caffeic acid based hybrids inhibiting acetylated and phosphorylated STAT3 protein. Eur J Med Chem. 2016 Nov 29;124 1006-1018.

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STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 values of 1.82 ?M and 2.14 ?M , respectively), induces tumor apoptosis.