Apoptosis

KT5823 View larger

KT5823

AT15670

CAS 126643-37-6

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$2,720.00

$2,720.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $1,224.00 Total: $122,400.00
150 $1,414.40 Total: $70,720.00
125 $1,659.20 Total: $41,480.00
110 $1,958.40 Total: $19,584.00
15 $2,312.00 Total: $11,560.00

Data sheet

Molecular FormulaC29H25N3O5
Molecular Weight495.53
CAS Numbers126643-37-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@]12N3C=4C5=C(C6=C(C4C=7C3=CC=CC7)CN(C)C6=O)C=8C(N5[C@](O1)(C[C@@]2(C(OC)=O)OC)[H])=CC=CC8
ReferencesGadbois DM, et al. Multiple kinase arrest points in the G1 phase of nontransformed mammalian cells are absent in transformed cells. Proc Natl Acad Sci U S A. 1992 Sep 15;89[18] 8626-30.

More info

KT5823 is a selective and potent cGMP-dependent protein kinase (PKG) inhibitor with inhibitory effects on PKA and PKC.KT5823 increases thyroid-stimulating hormone-induced (Na+I- symporter) NIS expression and iodide ion uptake by modulating sodium iodide symporter protein expression and activity in thyroid cells. KT5823 induces apoptosis.