Apoptosis

BI-6C9 View larger

BI-6C9

AT5827

CAS 791835-21-7

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$51.00

$51.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $22.95 Total: $2,295.00
150 $26.52 Total: $1,326.00
125 $31.11 Total: $777.75
110 $36.72 Total: $367.20
15 $43.35 Total: $216.75

Data sheet

Molecular FormulaC23H25N3O4S2
Molecular Weight471.59
CAS Numbers791835-21-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1ccc(cc1)S(=O)(=O)NCCCC(=O)Nc1ccc(Sc2ccc(N)cc2)cc1
ReferencesGrohm J , Plesnila N , Culmsee C . Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death[J]. Brain, Behavior, and Immunity, 2010, 24[5] 0-838.

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BI-6C9 is an inhibitor of tBid (Kd = 20 ?M).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.