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View larger Tubulin polymerization-IN-43
AT77647
CAS 2773345-90-5
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HOW TO ORDER
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $60.30 | Total: $6,030.00 |
| 1 | 50 | $69.68 | Total: $3,484.00 |
| 1 | 25 | $81.74 | Total: $2,043.50 |
| 1 | 10 | $96.48 | Total: $964.80 |
| 1 | 5 | $113.90 | Total: $569.50 |
Data sheet
| Molecular Formula | C17H13F4N3O |
| Molecular Weight | 351.3 |
| CAS Numbers | 2773345-90-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C)(C=1C2=C(N=C(C(F)(F)F)N1)C=CC(F)=C2)C3=CC=C(OC)C=C3 |
| References | Wu H, et al. Discovery of novel N-aryl-2-trifluoromethyl-quinazoline-4-amine derivatives as the inhibitors of tubulin polymerization in leukemia cells. Eur J Med Chem. 2023 Aug 5;256 115470. |
More info
Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.Tubulin polymerization-IN-43 has multiple effects, disrupting the cellular microtubule network by targeting the colchicine locus and promoting cell cycle arrest and apoptosis in leukaemia cells. Tubulin polymerisation-IN-43 has multiple effects, promoting leukaemia cell cycle arrest in G2M phase and apoptosis by targeting Colchicine sites to disrupt the cellular microtubule network.