Apoptosis

SR-4835 View larger

SR-4835

AT8325

CAS 2387704-62-1

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$43.00

$43.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $19.35 Total: $1,935.00
150 $22.36 Total: $1,118.00
125 $26.23 Total: $655.75
110 $30.96 Total: $309.60
15 $36.55 Total: $182.75

Data sheet

Molecular FormulaC21H20Cl2N10O
Molecular Weight499.36
CAS Numbers2387704-62-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCn1cc(cn1)-n1cnc2c(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)nc(nc12)N1CCOCC1
ReferencesQuereda V, et al. Therapeutic Targeting of CDK12CDK13 in Triple-Negative Breast Cancer. Cancer Cell. 2019 Oct 8. pii S1535-6108[19]30424-6.

More info

SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (TNBC) cells