Apoptosis

Sodium Oxamate View larger

Sodium Oxamate

AT19831

CAS 565-73-1

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Data sheet

Molecular FormulaC2H2NNaO3
Molecular Weight111.03
CAS Numbers565-73-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[Na+].NC(=O)C([O-])=O
ReferencesQiao T, et al. Inhibition of LDH-A by Oxamate Enhances the Efficacy of Anti-PD-1 Treatment in an NSCLC Humanized Mouse Model. Front Oncol. 2021 Mar 30;11 632364.

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Sodium Oxamate (Oxamic acid sodium salt) is an LDH inhibitor that specifically inhibits LDHA. Sodium Oxamate has antitumor activity and induces cell cycle arrest and apoptosis.