Autophagy

Telaglenastat View larger

Telaglenastat

AT6797

CAS 1439399-58-2

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$40.00

$40.00 per 5 mg

Data sheet

Molecular FormulaC26H24F3N7O3S
Molecular Weight571.57
CAS Numbers1439399-58-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeFC(F)(F)Oc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccn4)s3)nn2)c1
ReferencesGross MI, et al. Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer. Mol Cancer Ther. 2014 Apr;13[4] 890-901.

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Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC.