Autophagy

Deferoxamine Mesylate View larger

Deferoxamine Mesylate

AT1637

CAS 138-14-7

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$41.00

$41.00 per 100 mg

Data sheet

Molecular FormulaC26H52N6O11S
Molecular Weight656.79
CAS Numbers138-14-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCS(O)(=O)=O.CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN
ReferencesFujisawa K, et al. An iron chelation-based combinatorial anticancer therapy comprising deferoxamine and a lactate excretion inhibitor inhibits the proliferation of cancer cells. Cancer Metab. 2022 May 12;10[1] 8.

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Deferoxamine Mesylate (DFOM) is an iron chelator and ferroptosis inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1? levels and induces apoptosis.