Autophagy

AMDE-1 View larger

AMDE-1

AT23716

CAS 478043-30-0

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$71.00

$71.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $31.95 Total: $3,195.00
150 $36.92 Total: $1,846.00
125 $43.31 Total: $1,082.75
110 $51.12 Total: $511.20
15 $60.35 Total: $301.75

Data sheet

Molecular FormulaC18H8ClF6N3
Molecular Weight415.72
CAS Numbers478043-30-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeFC(F)(F)C1=NC2=NC(=CC=C2C(=C1)C(F)(F)F)C(C#N)C1=CC(Cl)=CC=C1
ReferencesGao Y, et al. Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy. Cell Death Dis. 2016 Aug 11;7[8] e2330.

More info

AMDE-1 is an autophagy modulator and triggers autophagy in an Atg5-dependent manner. AMDE-1 recruits Atg16 to the pre-autophagosomal site and causes LC3 lipidation.