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View larger Quisinostat dihydrochloride
AT6865
CAS 875320-31-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $22.50 | Total: $2,250.00 |
| 1 | 50 | $26.00 | Total: $1,300.00 |
| 1 | 25 | $30.50 | Total: $762.50 |
| 1 | 10 | $36.00 | Total: $360.00 |
| 1 | 5 | $42.50 | Total: $212.50 |
Data sheet
| Molecular Formula | C21H28Cl2N6O2 |
| Molecular Weight | 467.39 |
| CAS Numbers | 875320-31-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cl.Cn1cc(CNCC2CCN(CC2)c2ncc(cn2)C(=O)NO)c2ccccc12 |
| References | Arts J, et al. Clin Cancer Res, 2009, 15[22], 6841-6851. |
More info
Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.